1. You have identified an individual with a genetic mutation that prevents the actin protein from polymerizing in their melanocytes. Would you expect the structure of their melanocytes to differ from individuals who do not have this mutation? If so, describe how they would differ.
2. Considering what you know about transport across the cell membrane, describe all of the types of transport used in the transfer of mature melanosomes from a melanocyte to a keratinocyte as depicted in the zoomed-in region of figure 1.
3. What type of microscope would you use to study and observe mitochondria-melanosome tethering? Using no more than two sentences, explain your reasoning.
4. You identify an individual who does not express a functional microtubule-associated motor protein, dynein, within their melanocytes. Would you expect to find mature melanosomes in the keratinocytes of this individual? Using no more than two sentences, explain your reasoning.
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