
The overall objective for this assignment is to select a journal article relating to a non-communicable disease outcome in order to summarise the putative aetiological mechanism of the outcome, assess the evidence-base for the association, and to consider methodological limitations in the interpretation of the association. Question 1: Provide the reference of the article and indicate the following: The life-course model illustrated, and the period in the life-course to which the exposure relates. Summarise the hypothesized aetiological mechanism by which the exposure is associated with the outcome, Summarise the findings of the example article you selected. Question 2: Summarise the evidence-base that supports or does not support the association in the article you selected.Question 3: Summarise the key methodological limitations in interpreting the association described in Question 1, and assess the extent to which the observed association can be attributed to non-causal mechanisms.
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